Problem 1: (TLC)
1)Obtain a silica carbamide peroxide gel coated glass plate for the stationary phase and acidified ethyl acetate (0. 1% lactic acid in ethyl acetate) for the cellular phase. 2) Check out a developing jar from the preproom to run home plate and obtain four samples: pure aspirin, salicylic acid, an aspirin tablet and a great aspirin merchandise. 3) Chromatograph these four samples by simply spotting them on a TLC plate applying an open ended capillary tube. (Preparation of the aspirin tablet)
1) Grind up the tablet and transfer it to a centrifuge tube. 2) Add regarding 20 drops of a 50/50 mixture of ethanol and dichloromethane to the smashed tablet. Glass the conduit and shake the combination. 3) Allow it to stand for about 10 minutes allowing the aspirin to melt and the insoluble materials to settle. (Preparing the aspirin)
1) Put some over a watch glass and add a number of drops in the 50/50 blend of ethanol and dichloromethane. 2) Work the mixture which has a spatula to dissolve the aspirin. 3) Because acetylsalicylsaure is without color you will not find it on the menu. Two methods are used to see the spots on the plate. The first getting is to place the plate underneath the UV mild. Draw the style in your laboratory book. 4) The second method is to place home plate in the iodine chamber and leave it there for a few a few minutes. Remove and mark the spots. Problem 2:
In order to find the percent produce, we will likely need to find 3 calculations. The formula may be the experimental yield divided by the theoretical produce. 1) To find the percent deliver of raw product you determine the mass from the crude acetylsalicylsaure you measured. The assumptive yield is founded on the weight of the salicylic acid all of us used. 2) To find the percent yield of recrystallization, we discover the mass of the recrystallized aspirin. The theoretical produce will be the identical to for the crude deliver calculation. 3) To find the percent yield from the titration, we find the mass of the aspirin from the titration data furnished by the total mass of the test that...